Hydroxymethylglutaryl-CoA Reductase Inhibitors

Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis.

Also Known As:

HMG-CoA Reductase Inhibitors; Inhibitors, HMG-CoA Reductase; Inhibitors, Hydroxymethylglutaryl-CoA; Inhibitors, Hydroxymethylglutaryl-Coenzyme A; Statins; HMG CoA Reductase Inhibitor; HMG CoA Reductase Inhibitors; HMG-CoA Statins; Hydroxymethylglutaryl CoA Reductase Inhibitor; Hydroxymethylglutaryl CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Inhibitors; Hydroxymethylglutaryl-Coenzyme A Inhibitors; Inhibitors, HMG CoA Reductase; Inhibitors, Hydroxymethylglutaryl CoA; Inhibitors, Hydroxymethylglutaryl Coenzyme A; Inhibitors, Hydroxymethylglutaryl-CoA Reductase; Reductase Inhibitor, Hydroxymethylglutaryl-CoA; Reductase Inhibitors, HMG-CoA; Reductase Inhibitors, Hydroxymethylglutaryl-CoA; Statins, HMG CoA; HMG-CoA Reductase Inhibitor; Hydroxymethylglutaryl-CoA Reductase Inhibitor; Statin; Statins, HMG-CoA

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Therapeutic Uses: 47080
    - Lipid Regulating Agents: 18
      - Hypolipidemic Agents: 776
        Anticholesteremic Agents: 22
        Hydroxymethylglutaryl-CoA Reductase Inhibitors: 26301
  - Molecular Mechanisms of Pharmacological Action: 24
    - Enzyme Inhibitors: 1659
      - Hydroxymethylglutaryl-CoA Reductase Inhibitors: 26301
    - Antimetabolites: 1599
      - Hypolipidemic Agents: 776
        Anticholesteremic Agents: 22
        Hydroxymethylglutaryl-CoA Reductase Inhibitors: 26301

E R Pimentel Selected Research

E R Pimentel Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure